Documentary Research Article on Uterus Transplantations Using Deceased Donor Organs: A review to 2021
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Abstract
Reproductive technology reached a new high in 2017 with the birth of a baby girl using the uterus from a deceased donor. There were no unusual complications recorded with the procedure or with the health of the mother. Three years earlier, in Swedish trials, two boys were born from uteri taken from live donors, relatives of the mothers. Science had managed to cure absolute uterine factor fertility AUFI, in women so afflicted. While some fine tuning in procedure will dominate future development, especially the clinical aspects, we must not forget the ethical considerations. This documentary review therefore focuses on how deceased donor uterus transplantations are viewed within the available data in three contexts: the anthropology of the human, in medicine, and in sociology with emphasis on certain cultural constructs of modern liberal society. Underlying the diagnosis is the fact that the uterus is a non-vital organ in human physiology, and dead donor uterus transplantations or DD UTX raise new challenges in ethics. The biases observed in the data, the limitations; a procedure less than ten years old, and the conclusions we arrived at, are presented in this review.
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References
Bronnstrom M, Johannesen L, Bokstrom H, et al. Livebirth after uterus transplant. The Lancet [Internet]. 2015; 385:607-16. Version of Record. Disponible en: https://doi.org/10.1016/SO140-6736(14)61728-1
Diaz C, Pellicer A. First baby born via uterus transplant from a deceased donor. The Lancet [Internet]. 2018 dic; 392(10165):2657-58. [posted to EurekAlert System]. Disponible en: http://www.thelancet.com/journals/lancet/article/PIISOI40-6736(18)31766-5/fulltext
Cook M. First baby born from uterus of a deceased donor. Bioedge [Internet]. 2018 dic. Disponible en: https://www.bioedge.org/images/2008images/FB_brazil_womb_transplant.jpgbrazil
Aznar J. Uterus transplantation raises obvious ethical issues. Bioethics Observatory Institute of Life Sciences: Catholic University of Valencia; 2021. Disponible en: https://www.observatoriobioetica.org/2021/01/el-trasplante-de-utero-plantea-evidentes-problemas-eticos/35040
Ejzenberg D, Mendes LR, Haddad LB, Baracat ED, D’Albuquerque LA, Andraus, W. Uterine Transplantation: A systematic review. Clinics. 2016; 71(11):679-68.
Richards EG, Farrell RM, Ricci S. et al. Uterus transplantation: State of the art in 2021. J Assist Reprod Genet. 2021; 38:2251-2259. https://doi.org/10.1007/s10815-021-02245-7
Hammond-Browning N, Yao, SL. Deceased Donation Uterus Transplantation: A review. Transplantology. 2021; (2):140-148. https://doi.org/10.3390/transplantology2020014
Jarvholm S, Dahm-Kahler P, Kvarnstrom N, Brannstrom M. Straight out of the womb:The psychosocial implications of uterine transplant recipients and partners up to 3 years after transplantation: Results from the Swedish Trial. Fertil. Steril. 2020; 114:417-445. https://doi.org/10.1016/j.fertnstert.2020.04.060
Van Erp A C, van Dulleman LFA, Ploeg RJ, Leuvenink HGD. Systematic review on the treatment of deceased organ donors. Transplant. Rev. 2018; 32(4):194-206, https://doi.org/10.1016/j.trre.2018.06.001
Mahajan A, Wray C. Organ transplantation: A systematic review. Anesthesiol. Clin. 2017; 35(3):xv-xvi. https://doi.org/10.1016/j.anclin.2017.06.001
Naef S G. Iranian embryo donation, law and surrogacy regulations: The intersection of religion, law and ethics. Die Welt des Islams; Special Theme Issue: The social politics of Islamic bioethics. 2015; 55(3/4):348-377.
Guntram L, Williams N J. Positioning uterus transplantation as a ‘more ethical’ alternative to surrogacy: Exploring symmetries between uterus transplantation and surrogacy through analysis of a Swedish Government white paper; Bioethics Special Issue Uterus Transplants. 2018; 32(8):477-533. https://doi.10.1111/bioe.12469
O’Donovan L, Williams N J, Wilkinson S. Ethical and policy issues raised by uterus transplants. Invited review; British Medical Bulletin. 2019; 131:19-28. https://doi:10.1093/bmb/Idz022
Zazukhina V. Bioethics in transdisciplinary and interdisciplinary context of post non-classical science. Paper presented at: CBU international conference on innovation, technology transfer and education 2014. Proceedings of cbu International Conference; 2014 febrero; Prague, Czech Republic; 2014. Disponible en: http://dx.doi.org/10.12955/cbup.v2.464
Sgreccia E. Personalist bioethics: Foundations and applications. Philadelphia: National Catholic Bioethics Center; 2012:3-29.
May W E. Defining death and organ transplantation. Catholic Bioethics and the Gift of Human Life. Huntington Indiana; Our Sunday Visitor Publishing Co.; 2008; 319-320,353-356.
Catholic Church. Donum Vitae-The Gift of Life: Instruction on respect for human life in its origin and on the dignity of procreation: Washington DC; National Catholic Bioethics Center; 2000.
Catholic Church. Dignitas Personae: Instruction on certain bioethical questions. CDF; 2008. Disponible en: http://www.vatican.va
Ikels, C. The anthropology of organ transplantation. Ann. Rev. of Anthropology. 2013; (42):89-102. http://www.jstor.org/stable/43049292
Cunningham CP. Womb transplant babies: A preliminary exploration of recent biomedical advances. Dignitas. 2014; (4):1,4-7,12-13. Disponible en: http://www. cbhd.org
Ronchi FU, Napoletano G. Uterus Transplantation and the redefinition of core bioethics precepts. Acta biomedica; Atenei Parmensis. 2021; 92(5). https://doi.org/10.23750/abm.v92i5.12257
Spillman MA, Sade RM. A Woman in Full. Am. J. of Bioeth. 2018; 18:(7)32-34. https://doi.org/10.1080/15265161.2018.1
CaplanAL.Traffickingandmarketsinkidneys:Twopoorsolutionstoapressingprob- lem. In A. Akabayashi (ed), The future of bioethics: International dialogues; Oxford: Oxford University Press. 2014. p. 407-416. Disponible en: https://doi.org/10.1093/acprof:oso/978019968267.003.0053
Bruno B, Arora KS. Uterus Transplantation: The ethics of using deceased versus living donors. Am. J. Bioeth. 2018; 18:(7):6-15. https://doi.org/10.1080/15265161.2018.1